The Importance of Good Sleep

Dr. Jeffrey Iliff
by Flow Research Collective
August 1, 2023
Hyperarousal can become a permanent thing and prevents us from sleeping normally.
Dr. Jeffrey Iliff

Today, we are joined by neuroscientist Dr. Jeffrey Iliff. He focuses on neurodegeneration and traumatic brain injury research.

In the space of health consciousness, we tend to talk about nutrition, fitness, recovery, and sleep. But here at the Collective, we also consider sleep and recovery the foundation of your performance.

If you treat your life like a corporate athlete, then you want to make sure to train and rest like an athlete.

So, very early on in the conversation with Dr. Iliff we talk about accumulating sleep debt, jet lag, and sleep deprivation and what that means for the cleansing of the brain - or lack thereof.


In this episode, you will learn about:

  • Who is Jeffrey Iliff? (4:17)
  • The glymphatic system (5:13)
  • Sleep & cognitive performance (7:14)
  • What regulates sleep? (11:22)
  • Circadian regulation (13:19)
  • How do you align homeostatic drive and Circadian regulation? (15:15)
  • The Noradrenergic center (19:02)
  • Sleep quality on flow (22:36)
  • Can you pay back sleep? (28:30)
  • Cognitive sustainability (30:29)
  • The determining factor for how your brain is going to age (33:54)
  • Behaviors & habits that contribute to cognitive sustainability (38:45)
  • How to maintain a high performing brain (44:35)


Neuroscientist Jeff Iliff 's research follows the exploration of how the brain’s support cells, called glia, contribute to maintaining the proper environment for neuronal function and how their failure in conditions like vascular dementia, stroke, and traumatic brain injury leads to neurodegeneration and seeks to define the basic cellular mechanisms by which brain blood flow is coordinated up and down the vascular tree. Now an Assistant Professor of Anesthesiology and Perioperative Medicine at Oregon Health & Science University, Jeff was a part of a University of Rochester Medical Center team that discovered a brain cleansing system, which they dubbed the “glymphatic system.”


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